What Is Hexaconazole and Why Is It an Important Triazole Fungicide?

2025-08-19 15:01

Technical Introduction

Hexaconazole is a systemic triazole fungicide belonging to the demethylation inhibitor (DMI) group of fungicides. It is widely used in agriculture, horticulture, and plantation crops to control a broad spectrum of fungal diseases, especially those caused by Ascomycetes and Basidiomycetes.

The mode of action of Hexaconazole is the inhibition of ergosterol biosynthesis in fungal cell membranes. It blocks the enzyme C14-demethylase, disrupting membrane formation, leading to cell leakage and fungal death.

It is effective both as a protective and curative fungicide, making it highly valuable for integrated disease management.

Applications

  • Cereal Crops (Wheat, Rice, Maize, Barley):

    • Controls sheath blight, blast (rice), powdery mildew, rusts, and leaf spots.

  • Fruits (Mango, Banana, Grapes, Apple, Citrus):

    • Effective against powdery mildew, anthracnose, scab, and rust diseases.

  • Vegetables (Tomato, Potato, Peppers, Beans, Cucurbits):

    • Protects against early blight, powdery mildew, and leaf spot diseases.

  • Plantation Crops (Tea, Coffee, Rubber):

    • Extensively used in tea plantations for blister blight control.

    • Effective in coffee rust management.

  • Turf and Ornamentals:

    • Used to control powdery mildew, rusts, and leaf spots.

Advantages

  • Broad-Spectrum Fungicide: Active against a wide range of foliar diseases.

  • Systemic & Curative Action: Moves within the plant, controlling established infections.

  • Long Residual Activity: Provides extended protection, reducing spray frequency.

  • Versatile Applications: Suitable for cereals, fruits, vegetables, and plantations.

  • Effective in Tropical Climates: Performs well in humid and high-disease-pressure conditions.

  • Resistance Management: Works best when rotated or combined with strobilurins, SDHIs, or multi-site fungicides.

Specifications (Typical Parameters)

ParameterDescriptionTypical Value
Chemical Name(RS)-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-olHexaconazole
Chemical FormulaMolecular compositionC₁₄H₁₇Cl₂N₃O
Molecular Weight
~314.2 g/mol
AppearancePhysical stateWhite to off-white crystalline powder
Formulation TypesEmulsifiable Concentrate (EC), Suspension Concentrate (SC), Water-Dispersible Granules (WDG)Common: 5% EC, 25% EC
SolubilityIn water (25°C)~0.02 g/L (low solubility)
StabilityStable under normal conditionsSensitive to strong alkali
Mode of ActionDMI fungicide (C14-demethylase inhibitor)Protective & curative

FAQ

Q1: What is Hexaconazole mainly used for?
A: It is widely used in rice, tea, grapes, mango, and vegetables to control powdery mildew, rusts, anthracnose, and sheath blight.

Q2: Is Hexaconazole systemic?
A: Yes, Hexaconazole is a systemic fungicide, moving within plant tissues to protect new growth.

Q3: Can Hexaconazole cure diseases after infection?
A: Yes, it has curative action if applied shortly after infection, though it is most effective preventively.

Q4: How does Hexaconazole compare with Propiconazole or Tebuconazole?
A: All three are triazoles with similar modes of action, but Hexaconazole is particularly valued in rice and tea plantations, while Propiconazole is more common in cereals, and Tebuconazole in oilseeds and fruit crops.

Q5: How should Hexaconazole be applied?
A: Apply as a foliar spray at early signs of disease, ensuring good leaf coverage. Repeat applications based on disease pressure and local recommendations.

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