Cypermethrin: A Widely Used Synthetic Pyrethroid Insecticide

2025-08-21 15:29

Technical Introduction

Cypermethrin (IUPAC: [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-1-carboxylate) is a synthetic pyrethroid insecticide that has been extensively used in agriculture, forestry, veterinary medicine, and public health pest control.

It functions as a sodium channel modulator, disrupting normal nerve transmission in insects. By prolonging sodium channel opening, Cypermethrin causes repetitive nerve firing, paralysis, and death of target pests.

  • Mode of Action: Sodium channel modulator (IRAC Group 3A).

  • Systemicity: Non-systemic; acts primarily by contact and ingestion.

  • Target Spectrum: Broad-spectrum control of chewing and sucking pests including caterpillars, aphids, thrips, beetles, weevils, mites, mosquitoes, and flies.


Applications

  • Agriculture:

    • Effective on cotton, maize, rice, soybeans, wheat, vegetables, and fruit crops against bollworms, cutworms, stem borers, aphids, and thrips.

  • Public Health:

    • Used in vector control programs against mosquitoes, flies, cockroaches, and bedbugs.

  • Veterinary:

    • Incorporated into formulations for livestock ectoparasite control (ticks, lice, fleas, and flies).

  • Stored Products:

    • Protects grains, flour, and other stored commodities from beetle and moth infestations.


Advantages

  • Broad-Spectrum Activity: Kills both chewing and sucking insect pests.

  • Fast Knockdown Effect: Provides rapid mortality after application.

  • Residual Effect: Protects crops for several days to weeks depending on formulation.

  • Versatile Use: Applied in agriculture, veterinary, household, and public health sectors.

  • Resistance Management: Useful in rotation programs with other chemical classes.

  • Cost-Effective: Readily available and affordable compared to many newer insecticides.


Specifications (Typical Parameters)

ParameterDescriptionTypical Value
Chemical NameCypermethrin
Chemical ClassSynthetic Pyrethroid (IRAC 3A)
Chemical FormulaC₂₂H₁₉Cl₂NO₃
Molecular Weight~416.3 g/mol
AppearanceYellowish to brown viscous liquid
Purity (TC)≥ 92%
Common FormulationsEmulsifiable concentrate (EC), wettable powder (WP), suspension concentrate (SC), oil-in-water emulsions10% EC, 25% EC, 50% EC, 5% WP
Mode of ActionSodium channel modulator; contact and stomach poison
Target PestsCaterpillars, beetles, aphids, thrips, flies, mosquitoes, ticks, cockroaches
Residual Activity7–15 days depending on crop and environment
ToxicityModerate mammalian toxicity (oral LD₅₀ in rats ~250–400 mg/kg); highly toxic to fish, bees, and aquatic organisms

FAQ

Q1: How does Cypermethrin kill insects?
A: It acts on sodium channels in insect nerve cells, causing hyperexcitation, paralysis, and death.

Q2: Is Cypermethrin systemic?
A: No. It is non-systemic, working mainly by contact and ingestion.

Q3: What crops is Cypermethrin commonly used on?
A: It is widely applied on cotton, maize, rice, wheat, soybeans, vegetables, and fruit crops.

Q4: How long does Cypermethrin protect crops after spraying?
A: Residual activity lasts 7–15 days, depending on weather, crop, and pest pressure.

Q5: Is Cypermethrin safe for bees?
A: No. It is highly toxic to bees, fish, and aquatic organisms. Applications should avoid flowering periods and water contamination.

Q6: How does Cypermethrin compare to Fenvalerate or Fenpropathrin?
A: - Fenvalerate is more focused on chewing insects.

  • Fenpropathrin is effective on both insects and mites.

  • Cypermethrin has broader insecticidal activity and is more widely used in public health and veterinary fields.

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