How 3,5,6-Trichloropyridin-2-ol Sodium (NATCP) Enhances Agricultural Fungicide Formulations

Introduction to 3,5,6-Trichloropyridin-2-ol Sodium (NATCP)
3,5,6-Trichloropyridin-2-ol Sodium, commonly known as NATCP, is a high-purity (87.5%) sodium salt derivative of 3,5,6-trichloropyridinol. It is widely used as an intermediate or active ingredient in the production of agricultural fungicides and bactericides. NATCP plays a crucial role in improving the efficiency and stability of formulations targeting crop protection.

Chemical Properties and Mode of Action
NATCP is characterized by its molecular structure containing a pyridin-2-ol ring with three chlorine atoms at positions 3, 5, and 6. The sodium salt form enhances its solubility and stability in aqueous solutions. NATCP acts primarily as a fungicidal agent by disrupting fungal cellular metabolism, thereby inhibiting spore germination and mycelial growth in various pathogenic fungi.

Applications in Crop Protection
NATCP is mainly used as an intermediate in synthesizing systemic fungicides like chlorothalonil and other chlorinated pyridine derivatives. These fungicides are applied to a broad range of crops including cereals, fruits, vegetables, and ornamentals to control fungal diseases such as powdery mildew, leaf spot, and rust. By improving the formulation’s stability and efficacy, NATCP contributes to more effective disease control and increased crop yields.

Benefits of Using NATCP

• High purity (87.5%) ensures consistent quality and performance in formulations.

• Enhanced solubility facilitates easy mixing and uniform application in spray solutions.

• Improved fungicidal activity when incorporated into finished products.

• Supports systemic fungicides with better uptake and translocation in plants.

Safety and Environmental Considerations
While NATCP is a valuable chemical intermediate, it must be handled with care. It is moderately toxic if ingested or inhaled and may cause skin or eye irritation. Proper personal protective equipment (PPE) should be used during handling. Environmental exposure should be minimized to prevent aquatic toxicity, and disposal should comply with local regulations.

Handling and Storage Recommendations
Store NATCP in a cool, dry, and well-ventilated area away from incompatible substances such as strong acids or oxidizers. Keep containers tightly closed to avoid moisture absorption and contamination. Follow all safety data sheet (SDS) guidelines for transport and storage.

FAQ About 3,5,6-Trichloropyridin-2-ol Sodium (NATCP)

Q1: What is the primary use of NATCP?
It is mainly used as an intermediate in manufacturing fungicides and bactericides for crop protection.

Q2: How pure is the NATCP product typically?
The product usually has a purity of 87.5%, which ensures high-quality formulation inputs.

Q3: Is NATCP directly applied to crops?
No, NATCP is typically not used directly but rather as a chemical intermediate in the synthesis of fungicidal products.

Q4: What precautions are necessary when handling NATCP?
Wear protective gloves, masks, and goggles to avoid skin and respiratory exposure. Work in well-ventilated areas.

Q5: Can NATCP affect the environment?
Yes, it is moderately toxic to aquatic life, so spills and runoff must be controlled carefully.