Ethylhexylglycerin (INCI: Ethylhexylglycerin) is a synthetic derivative of glycerin widely used in cosmetics and personal care products. It functions primarily as a skin-conditioning agent, emollient, deodorizing additive, and preservative enhancer.
Chemical Name: 3-(2-ethylhexyloxy)-1,2-propanediol
CAS Number: 70445-33-9
Chemical Family: Alkyl glyceryl ethers
Mode of Action:
Antimicrobial booster — weakly antimicrobial on its own, but significantly enhances the efficacy of preservatives like phenoxyethanol, parabens, or organic acids.
Deodorant function — inhibits odor-causing bacteria by interfering with bacterial cell membranes.
Skin conditioning — provides smooth, non-greasy skin feel.
Cosmetics & Personal Care
Skin creams, lotions, serums
Shampoos, conditioners, hair sprays
Deodorants and antiperspirants
Baby care products
Makeup products
Preservation Systems
Used in “paraben-free” and “formaldehyde-free” formulations as part of mild preservative blends.
Often combined with phenoxyethanol (e.g., the commercial blend “Euxyl® PE 9010”).
Dermatological Preparations
Incorporated into medicated creams and gels due to low irritation potential.
Mild & skin-friendly compared to stronger preservatives.
Preservative boosting effect reduces the need for high concentrations of traditional preservatives.
Excellent deodorizing activity without blocking pores.
Moisturizing & emollient properties for improved skin feel.
Stable over a wide pH range (4–8) → suitable for most cosmetic formulations.
Versatile solubility in both water and oil systems with emulsifiers.
Suitable for sensitive-skin products, including baby care.
Parameter | Specification |
---|---|
Chemical Name | Ethylhexylglycerin |
CAS Number | 70445-33-9 |
Molecular Formula | C₁₁H₂₄O₃ |
Molecular Weight | 204.31 g/mol |
Appearance | Clear, colorless to pale yellow liquid |
Odor | Nearly odorless |
Solubility | Soluble in alcohol, glycols; dispersible in water |
pH Range (in use) | 4.0 – 8.0 |
Recommended Dosage | 0.3 – 1.0% in formulations |
Shelf Life | 24 months (sealed container, cool/dry storage) |
Safety Profile:
Considered safe and non-irritating at recommended use levels.
Suitable for sensitive skin formulations.
Regulatory Status:
Approved for cosmetic use in EU, US (FDA), Japan, China, and other regions.
Not subject to maximum concentration restrictions (used as multifunctional additive rather than primary preservative).
Irritation Potential: Very low compared to parabens or isothiazolinones.
Q1: Is ethylhexylglycerin a preservative?
Not exactly. It is a preservative enhancer — mildly antimicrobial on its own, but primarily boosts the performance of other preservatives.
Q2: Why is ethylhexylglycerin common in “paraben-free” products?
Because it provides gentle preservation support while avoiding controversial parabens and formaldehyde-releasers.
Q3: Can ethylhexylglycerin replace preservatives entirely?
No. It is usually used in combination with stronger preservatives such as phenoxyethanol, organic acids, or benzyl alcohol.
Q4: Is it safe for sensitive skin and baby products?
Yes. Due to its low irritation potential, it is widely used in sensitive-skin creams, baby wipes, and baby lotions.
Q5: How does ethylhexylglycerin work in deodorants?
It suppresses odor-causing bacteria on skin without interfering with natural perspiration, making it a gentle alternative to antiperspirants.